The Drug Codeine :: essays research papers

The Drug Codeine We used several different sources to gather our information. We go information from Jay Moser and Sue Peterson, our two local pharmacists. We researched medical encyclopedias, journals, and magazines. Codeine is known medically as methylmorphine. It is a drug derived from opium, a poppy plant. It was discovered in 1832 by French chemist Pierre-Jean Robiquet. Codeine constitutes about 0.5 to 2.5 percent of this plant substance. The drug has been in use since the early 1900's and it shares most of the pharmacologic characteristics of morphine, the other alkaloid in opium. Codeine is classified as a narcotic, it has the same painkiller effect as morphine but is only one-sixth to one-tenth as strong. Codeine occurs as a colorless or white crystals or as a white, crystalline powder and is slightly soluble in water and freely soluble in alcohol. The phosphate and sulfate salts of codeine occur as white, needle- shaped crystals or white, crystalline powders. Why is it used? Codeine is most useful in the relief of mild to moderate pain. It is also used as a cough remedy because it suppresses the part of the brain that triggers coughing, and as an anti-diarrheal drug, because it slows down muscle contractions in the intestinal wall. There are possible adverse effects. The most frequently observed adverse reactions include lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. These effects seem to be more prominent in ambulatory patients and in those who are not suffering severe pain. Other adverse reactions include the following: (1) Central Nervous System- Euphoria, dysphoria, weakness, headache, insomnia, agitation, disorientation, and visual disturbances. (2) Gastrointestinal- Dry mouth, anorexia, constipation, and biliary tract spasm. (3) Cardiovascular- Flushing of the face, abnormally slow heartbeat, faintness, and syncope. (4) Genitourinary- Urinary retention of hesitancy, anti-diuretic effect. (5) Allergic- skin rashes. Most drug manufactors list specific warnings to be aware of when taking codeine. (1) Codeine sulfate can produce drug dependence of the morphine type, and therefore has the potential for being abused psychic dependence, physical dependence and tolerance may develop upon repeated administration of Codeine. (2) Codeine may impair the mental and or physical abilities required for the performance of potentially hazardous tasks such as driving a car or operating machinery. (3) Patients receiving other narcotic painkillers, general anesthetics, tranquilizers, or other central nervous system depressants, including alcohol with codeine may exhibit an additive central nervous system depression. Who shouldn't take codeine? Pregnant women should not use codeine because safe use in pregnancy has not been established. Children below the age of three shouldn't be given this drug for that age group hasn't been established. Codeine should be given with caution to certain patients such as the elderly or